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The past, present and future of de novo protein design
RFdiffusionanfinsens-hypothesisPDBactivation-maximizationChromaescherichia-colimasked-language-models3D-crystal1D-fibre2D-lattice9OP9NCAAbeta-barrelTop7TIM-barrelprotein-language-modelsrosettananoporemacrocycleoligoamideBindCraftProGenPXDesignaffinityTNFscFvVHHCDRHELM-GPTRFpeptidesIDRPepPrCLIPaffinity-handlebeta-cateninSS18-SSX1beta-amyloidtau-proteinglycoproteinsoligomerizationFGFendocytosistranscytosisEndoTagsdigoxigeninmethotrexateCIDkemp-eliminationretro-aldolluciferasePLACERserineCRISPR-Caszinc-fingers
Research notes on The past, present and future of de novo protein design.