https://www.vishalv.com/tags/tiedmpnn Personal website of Vishal V, featuring writing, ideas, projects, and research en-us vishalvignesh.iitm@gmail.com (Vishal V) vishalvignesh.iitm@gmail.com (Vishal V) Wed, 23 Sep 2026 00:00:00 GMT https://www.vishalv.com/notes/shidaNovoDesignAllosterically2026 https://www.vishalv.com/notes/shidaNovoDesignAllosterically2026 The ability of enzymes to sense signals and respond by changing their structure and activity underlies cellular processes from signaling to metabolic control. While there have been recent advances in the de novo design of enzymes and conformationally switching proteins, combining... Wed, 23 Sep 2026 00:00:00 GMT vishalvignesh.iitm@gmail.com (Vishal V) tiedmpnn